Methylcinnamic Acid - China

CAS 1866-39-3

EinecsNo 217-479-9

Molecular Formula C10H10O2 Molecular weight 162.19 Purity 99%

LogP 2.09280 PSA 37.30000 Quality standard Enterprise standard

Melting point 196-198 degree C

Boiling point 300.6 degree C at 760 mmhg

Flash point 206.1 degree C

Density 1.147 g/cm3 Vapor pressure 0.000494mmhg at 25 degree C

Physical property Insoluble in water, Soluble in organic solvent like ethanol or ethyl acetate

Appearance White crystal Stability Stable under normal temperatures and pressures

Storage Store in a cool, dry place.

Store in a tightly closed container

Synonyms 4-Methylciamicacid;P-meth ycinnamic acid;BASF Luwipal 044;3-(4-methylphenyl)-2- propenoic acid;3-(p-Tolyl)acrylic acid;trans-4-methylcinnam ic acid;P-METHYLCINNAMIC ACID;2-Propenoic acid, 3-(4-methylphenyl)-;3-P-T OLYL-ACRYLIC ACID;RARECHEM BK HC T309;(2E)-3-(4-methylphen yl)prop-2-enoic acid;4-MethylcinnaMic Acid Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.

Description: 5-Methoxycinnamic acid is a photosensitive compound, also known as para-methoxycinnamate or O-methyl-p-coumarate, belongs to the class of organic compounds known as cinnamic acids.

These are organic aromatic compounds containing a benzene and a carboxylic acid group forming 3-phenylprop-2-enoic acid.

4-Methoxycinnamic acid exists as a solid and is considered to be practically insoluble (in water) and relatively neutral.

4-Methoxycinnamic acid has been detected in multiple biofluids, such as urine and blood.

Within the cell, 4-methoxycinnamic acid is primarily located in the membrane (predicted from logP).

Outside of the human body, 4-methoxycinnamic acid can be found in turmeric and wild celery.

This makes 4-methoxycinnamic acid a potential biomarker for the consumption of these food products.

Main Applications: 1 - methyl cinnamic acid is mainly used as an important intermediate in organic synthesis.

2 - p-MCA exerted antihyperglycemic/hypogly cemic effect by stimulating insulin secretion from pancreas and could be developed into a new potential for therapeutic agent used in type 2 diabetic patients.

3 - methyl cinnamic acid shows various pharmacologic actions such as hepatoprotective and antihyperglycemic activities, it also can stimulate insulin secretion from pancreatic β-cells by increasing Ca2+ influx via the L-type Ca2+ channels, but not through the closure of ATP-sensitive K+ channels.

4.4-Methoxycinnamic acid can strongly inhibit the diphenolase activity of mushroom tyrosinase, with the IC 50 value of 0.42 mM, and the inhibition is reversible.

5 - Inhibitory effects of cinnamic acid and its derivatives on the diphenolase activity of mushroom ( Agaricus bisporus ) tyrosinase.

6 - Natural products modulate Shigella-host-cell interaction.

7 - Photosensitive semiconductor nanocrystals, photosensitive composition comprising semiconductor nanocrystals and method for forming semiconductor nanocrystal pattern using the same

8 - Mechanisms of p-methoxycinnamic acid-induced increase in insulin secretion.

9 - Protective effect of p-methoxycinnamic acid, an active phenolic acid against 1, 2-dimethylhydrazine-induc ed colon carcinogenesis: modulating biotransforming bacterial enzymes and xenobiotic metabolizing enzymes.

Company Contact:

• Posted By: Wuhan LANDMARK Industrial Co., Ltd.

• Phone: 027-83916065

• Address: Tazi E. Road, No.18 Jiangan District Wuhan City, Wuhan , Hubei , China

• Email:

• Website: https://www.landmarkind.com

• Business Description: Wuhan LANDMARK Industrial Co., Ltd. was established in 2012 and is located in the sub-provincial-level central city of six provinces in central China - Wuhan City, Hubei Province.