Cotinine Cot Rapid Tests - China

Cotinine (COT) Rapid Tests

The COT Rapid Test is a rapid chromatographic immunoassay for the detection of Cotinine in human urine/saliva.

This test will detect other related compounds, please refer to the Analytical Specificity table in this package insert.

Cotinine is the first-stage metabolite of nicotine, a toxic alkaloid that produces stimulation of the autonomic ganglia and central nervous system when in humans.

Nicotine is a drug to which virtually every member of a tobacco-smoking society is exposed whether through direct contact or second-hand inhalation.

In addition to tobacco, nicotine is also commercially available as the active ingredient in smoking replacement therapies such as nicotine gum, transdermal patches and nasal sprays.

In a 24-hour urine, approximately 5% of a nicotine dose is excreted as unchanged drug with 10% as cotinine and 35% as hydroxycotinine; the concentrations of other metabolites are believed to account for less than 5%.

1 While cotinine is thought to be an inactive metabolite, it's elimination profile is more stable than that of nicotine which is largely urine pH dependent.

As a result, cotinine is considered a good biological marker for determining nicotine use.

The plasma half-life of nicotine is approximately 60 minutes following inhalation or parenteral administration.

2 Nicotine and cotinine are rapidly eliminated by the kidney; the window of detection for cotinine in urine at a cutoff level of 500 ng/mL is expected to be up to 2-3 days after nicotine use.

Well Biotect is an Alcohol Rapid Tests Company.

Company Contact:

• Posted By: Jiangsu Well Biotech Co., Ltd.

• Phone: 86 519 80191660

• Address: F4, C1 Building, No.9 Changyang Rd., Changzhou , Jiangsu , China

• Email:

• Website: https://www.wellbioscience.com/

• Business Description: Jiangsu Well Biotech Co., Ltd. - a Sino-American joint venture, is a professional manufacturer specialized in medical in vitro diagnostic assays and reagents, instrument research and development, and world-class sales and service, Well Biotech was established in 2006 located in No 9, Changyang Rd., Changzhou, Jiangsu China.
  
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